2-Hydrazinopyridine → HCID 21097342, compound

Reaction equation

O=C(CC)CC(OCC)=O.[N:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[NH:17][NH2:18].[CH:19]1([C:22]2N(C(C)C)N=[CH:24][C:23]=2[CH:30]=[O:31])C[CH2:20]1>>[CH2:19]([C:22]1[N:17]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][N:11]=2)[N:18]=[CH:24][C:23]=1[CH:30]=[O:31])[CH3:20]

Participants

Reactant 3

HCID 786452-Hydrazinopyridine

HCID 78656Ethyl 3-oxovalerate

HCID 196201355-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehyde

Product 1

HCID 21097342HCID 21097342, compound

Procedure

5-Ethyl-1-pyridin-2-yl-1H-pyrazole-4-carbaldehyde was prepared from ethyl 3-oxo-pentanoate and 2-pyridyl hydrazine in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49).

Sources & evidence

ORD record: ord-cad056e0e1404ca3985ca36922c35544
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07214802B2

Reaction notes

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