2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde → 2-(1-Benzyloxy-cyclopropyl)-3-methyl-3H-imidazole-4-carbaldehyde

Reaction equation

[CH2:1]([O:8]C1(C(N)=O)CC1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:15]1([C:18]2[N:22]([CH3:23])[C:21]([CH:24]=[O:25])=[CH:20][N:19]=2)[CH2:17][CH2:16]1>>[CH2:1]([O:8][C:15]1([C:18]2[N:22]([CH3:23])[C:21]([CH:24]=[O:25])=[CH:20][N:19]=2)[CH2:17][CH2:16]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

HCID 588613331-Benzyloxy-cyclopropanecarboxylic acid amide

Product 1

HCID 210972512-(1-Benzyloxy-cyclopropyl)-3-methyl-3H-imidazole-4-carbaldehyde

Procedure

2-(1-Benzyloxy-cyclopropyl)-3-methyl-3H-imidazole-4-carbaldehyde was prepared from 1-benzyloxy-cyclopropanecarboxylic acid amide in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record: ord-e6d86a0f811e49d59af579736d7c3982
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07214802B2

Reaction notes

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