3,5-Dimethyl-4-hydroxybenzaldehyde → (E)-3-(3,5-Dimethyl-4-hydroxyphenyl)2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile
Reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([CH3:11])[C:9]=1[OH:10])[CH:5]=O.[C:12]1([CH2:18][CH2:19][CH2:20][NH:21][S:22]([CH2:25][C:26]#[N:27])(=[O:24])=[O:23])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:1][C:2]1[CH:3]=[C:4](/[CH:5]=[C:25](/[S:22]([NH:21][CH2:20][CH2:19][CH2:18][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)(=[O:24])=[O:23])\[C:26]#[N:27])[CH:7]=[C:8]([CH3:11])[C:9]=1[OH:10]Participants
3
Procedure
M45 was prepared with 3,5-dimethyl-4-hydroxybenzaldehyde and N-3-phenyl-n-propyl cyanomethylsulfonamide under similar conditions as decribed for M40 (part B).
Sources & evidence
- ORD record
- ord-de4567a717b94b12a29b5d364df6b222
- Source dataset
- uspto-grants-2007_05