5-Chloro-4-nitro-thiophene-2-sulfonic acid (2-hydroxy-ethyl)-methyl-amide → 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid {2-chloro-5-[(2-hydroxy-ethyl)-methyl-sulfamoyl]-thiophen-3-yl}-amide

Reaction equation

[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[OH:14])([F:25])[F:26].[OH:27][CH2:28][CH2:29][N:30]([S:31](=[O:32])(=[O:33])[c:34]1[s:35][c:36]([Cl:42])[c:37]([N+:39]([O-:40])=[O:41])[cH:38]1)[CH3:43]>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[NH:39][c:37]1[c:36]([Cl:42])[s:35][c:34]([S:31]([N:30]([CH2:29][CH2:28][OH:27])[CH3:43])(=[O:32])=[O:33])[cH:38]1)([F:25])[F:26]