Benzo-1,3-dioxole-5-methylamine → 2-Amino-4-[(benzo [1,3]dioxol-5-ylmethyl)-amino]-6-furan-2-yl-pyrimidine-5-carbonitrile

HRID 1356005

Reaction equation

HRID 1356005 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[CH2:18]([NH2:28])[C:19]1[CH:27]=[CH:26][C:25]2[O:24][CH2:23][O:22][C:21]=2[CH:20]=1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([NH:28][CH2:18][C:19]2[CH:27]=[CH:26][C:25]3[O:24][CH2:23][O:22][C:21]=3[CH:20]=2)[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

4

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 99022562-Amino-4-[(benzo [1,3]dioxol-5-ylmethyl)-amino]-6-furan-2-yl-pyrimidine-5-carbonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and piperonylamine in DME. ES-MS m/e (%): 336 (M+H+, 100).

Sources & evidence

ORD record
ord-182b66832b3e42cf80137643acec4e4c
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Linked notes

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