1,2-Ethanediamine, N1-phenyl- → 6-Amino-2-furan-2-yl-4-(2-phenylamino-ethylamino)-nicotinonitrile

HRID 1356023Notes

Reaction equation

HRID 1356023 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](OS(C(F)(F)F)(=O)=O)[CH:3]=1.[C:23]1([NH:29][CH2:30][CH2:31][NH2:32])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>COCCOC>[NH2:1][C:2]1[CH:3]=[C:4]([NH:32][CH2:31][CH2:30][NH:29][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

4

Reactant 2

HCID 742701,2-Ethanediamine, N1-phenyl-HCID 86583754Trifluoromethanesulfonic acid 6-amino-3-cyano-2-furan-2-yl-pyridin-4-yl ester

Product 1

HCID 185076456-Amino-2-furan-2-yl-4-(2-phenylamino-ethylamino)-nicotinonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From trifluoromethanesulfonic acid 6-amino-3-cyano-2-furan-2-yl-pyridin-4-yl ester and N-phenylethylenediamine in DME. ES-MS m/e (%): 320 (M+H+, 100).

Sources & evidence

ORD record
ord-ed71f2c2623c411d832825751a9c3559
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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