[5-(Trifluoromethyl)pyridin-2-yl]methanamine → HCID 18507348, compound

HRID 1356076

Reaction equation

HRID 1356076 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[F:18][C:19]([F:29])([F:28])[C:20]1[CH:21]=[CH:22][C:23]([CH2:26][NH2:27])=[N:24][CH:25]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([NH:27][CH2:26][C:23]2[CH:22]=[CH:21][C:20]([C:19]([F:29])([F:18])[F:28])=[CH:25][N:24]=2)[N:3]=1

Participants

4

Reactant 2

HCID 3796375[5-(Trifluoromethyl)pyridin-2-yl]methanamineHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 18507348HCID 18507348, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and C-(5-trifluoromethyl-pyridin-2-yl)-methylamine in DME. ES-MS m/e (%): 361 (M+H+, 100).

Sources & evidence

ORD record
ord-fbbb571d945e4e2da2ce9e0dff6087b7
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Linked notes

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