Sodium Hydroxide → HCID 178437663, compound
Reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5]([F:9])=[C:4]([CH2:10][CH3:11])[N:3]=1.[OH-:12].[Na+]>O>[NH4+:3].[Cl:1][C:2]1[N:7]=[C:6]([OH:12])[C:5]([F:9])=[C:4]([CH2:10][CH3:11])[N:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 90 °C
Procedure
A mixture of the compound of part (ii) (40 kg) and water (10 kg) was heated to 90° C. and 4N aqueous sodium hydroxide solution (127 L) added.
Sources & evidence
- ORD record
- ord-629046f68d5c46e688cf6fbd48b1593b
- Source dataset
- uspto-grants-2003_07
- Patent number
- US06586594B1
Reaction notes
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