Diazomethane → N-acetyl-D-alanine

HRID 1357341Notes

Reaction equation

[N+](=C)=[N-].C[O:5][C:6](=[O:13])[C@H:7]([CH3:12])[NH:8][C:9](=[O:11])[CH3:10]>>[C:9]([NH:8][C@@H:7]([C:6]([OH:13])=[O:5])[CH3:12])(=[O:11])[CH3:10]

Participants

Reactant 2

HCID 9550Diazomethane

HCID 6951030(S)-Methyl 2-acetamidopropanoate

Product 1

HCID 132213N-acetyl-D-alanine

Procedure

A sample was treated with diazomethane to make the methyl ester before analysis. See Example 14 (N-acetyl alanine methyl ester) for analytical details.

Sources & evidence

ORD record: ord-3e3e7d952da4453f950834555dfb8db2
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06590115B2

Reaction notes

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