2-Aminopyridine → 2-(3,4-Dimethoxyphenyl)imidazo[1,2-a]pyridine

HRID 1358247

Reaction equation

HRID 1358247 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:8][O:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:13](=O)[CH2:14]Br>>[CH3:8][O:9][C:10]1[CH:11]=[C:12]([C:13]2[N:1]=[C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][N:3]3[CH:14]=2)[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 104392-AminopyridineHCID 2704232-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-one

Product 1

HCID 6592462-(3,4-Dimethoxyphenyl)imidazo[1,2-a]pyridine

Procedure

The title compound, pale yellow solid, m.p. 96° C. and MS: m/e=254.1 (M+), was prepared in accordance with the general method of example 1 from 2-amino-pyridine and 3,4-dimethoxy-phenacylbromide.

Sources & evidence

ORD record
ord-10901c37874f42a999e60123185b43c1
Source dataset
uspto-grants-2003_07
Patent number
US06596731B2

Linked notes

Loading…