3-(2-Methoxy-5-nitro-phenoxy)-1-methyl-pyrrolidine → HCID 18180176, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][C:4]=1[O:5][CH:6]1[CH2:10][CH2:9][N:8]([CH3:11])[CH2:7]1>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][C:4]=1[O:5][CH:6]1[CH2:10][CH2:9][N:8]([CH3:11])[CH2:7]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of 3-(2-methoxy-5-nitro-phenoxy)-1-methyl-pyrrolidine (3.0 g, 0.12 mmol) in ethanol (50 ml) was hydrogenated over 10% palladium on charcoal catalyst for 2 hrs to afford the title compound (D25). Found MH+ 223.
Sources & evidence
- ORD record
- ord-455edff6388e416b84a65a0b78b33a0c
- Source dataset
- uspto-grants-2003_07
- Patent number
- US06599904B2
Reaction notes
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