Acetone → 1-(4-bromo-2-fluorobenzyl)-2-(n-propyl)-4-ethyl-5-(2-(phenoxy)phenoxy)acetyl-1H-imidazole

HRID 136072

Reaction equation

HRID 136072 reaction equation
[Br:21][c:22]1[cH:23][c:24]([F:43])[c:25]([CH2:26][n:27]2[c:28]([CH2:38][CH2:39][CH3:40])[n:29][c:30]([CH2:36][CH3:37])[c:31]2[C:32]([CH2:33][Br:34])=[O:35])[cH:41][cH:42]1.[CH3:45][C:46](=[O:47])[CH3:48].[K+:15].[K+:16].[O-:17][C:18]([O-:19])=[O:20].[OH2:44].[OH:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[CH2:33][C:32]([c:31]1[n:27]([CH2:26][c:25]2[c:24]([F:43])[cH:23][c:22]([Br:21])[cH:42][cH:41]2)[c:28]([CH2:38][CH2:39][CH3:40])[n:29][c:30]1[CH2:36][CH3:37])=[O:35]

Participants

7

Reactant 6

HCID 180AcetoneHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 754912-Hydroxydiphenyl etherHCID 194304911-(4-bromo-2-fluorobenzyl)-2-(n-propyl)-4-ethyl-5-bromoacetyl-1H-imidazole

Product 1

HCID 194304711-(4-bromo-2-fluorobenzyl)-2-(n-propyl)-4-ethyl-5-(2-(phenoxy)phenoxy)acetyl-1H-imidazole

Sources & evidence

ORD record
ord-d51d4e7b4b3840ecbcfdc1e10bbeb60b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…