Ethyl 2-(2-aminothiazol-5-ylthio)acetate → {2-[3-(4-Methanesulfonyl-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-5-ylsulfanyl}-acetic Acid Ethyl Ester
Reaction equation
[CH3:1][S:2]([C:5]1[CH:26]=[CH:25][C:8]([O:9][C:10]2[CH:11]=[C:12]([CH:16]=[C:17]([O:19][C@@H:20]([CH3:24])[CH2:21][O:22][CH3:23])[CH:18]=2)[C:13]([OH:15])=O)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[CH2:27]([O:29][C:30](=[O:39])[CH2:31][S:32][C:33]1[S:37][C:36]([NH2:38])=[N:35][CH:34]=1)[CH3:28]>>[CH2:27]([O:29][C:30](=[O:39])[CH2:31][S:32][C:33]1[S:37][C:36]([NH:38][C:13](=[O:15])[C:12]2[CH:16]=[C:17]([O:19][C@@H:20]([CH3:24])[CH2:21][O:22][CH3:23])[CH:18]=[C:10]([O:9][C:8]3[CH:7]=[CH:6][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:26][CH:25]=3)[CH:11]=2)=[N:35][CH:34]=1)[CH3:28]Participants
3
Procedure
The title compound was prepared from 3-(4-methanesulfonyl-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A
Sources & evidence
- ORD record