N-Acetylsulfanilyl chloride → N-(4-(N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)sulfamoyl)phenyl)acetamide

HRID 136792

Reaction equation

HRID 136792 reaction equation
[C:20]([CH3:21])(=[O:22])[NH:23][c:24]1[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][c:4]([NH2:19])[cH:5][n:6][c:7]1[O:8][c:9]1[n:10][cH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]2[cH:18]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:19][S:30]([c:27]2[cH:26][cH:25][c:24]([NH:23][C:20]([CH3:21])=[O:22])[cH:29][cH:28]2)(=[O:31])=[O:32])[cH:5][n:6][c:7]1[O:8][c:9]1[n:10][cH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]2[cH:18]1

Participants

3

Reactant 2

HCID 8481N-Acetylsulfanilyl chlorideHCID 687937575-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 24852477N-(4-(N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)sulfamoyl)phenyl)acetamide

Sources & evidence

ORD record
ord-6f3d48bb4929410a8ff0b4afda125600
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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