2-Chloro-N-(2,6-dimethylphenyl)acetamide → 4-(2-Chloroacetylamino)phenyl acetate

Reaction equation

C[C:2]1[CH:7]=[CH:6][CH:5]=[C:4](C)[C:3]=1[NH:9][C:10](=[O:13])[CH2:11][Cl:12].[C:14]([O:17]C1C=CC(N)=CC=1)(=[O:16])[CH3:15]>>[C:14]([O:17][C:6]1[CH:7]=[CH:2][C:3]([NH:9][C:10](=[O:13])[CH2:11][Cl:12])=[CH:4][CH:5]=1)(=[O:16])[CH3:15]

Participants

Reactant 2

HCID 707982-Chloro-N-(2,6-dimethylphenyl)acetamide

HCID 83783Phenol, 4-amino-, 1-acetate

Product 1

HCID 225916104-(2-Chloroacetylamino)phenyl acetate

Procedure

Compound 56 was prepared in the manner of compound 3 substituting compound 55 for compound 1 in part A of Example 1.

Sources & evidence

ORD record: ord-4e33e54f037c44209c70a0c42e83e0e7
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573264B1

Reaction notes

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