Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

Reaction equation

[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

Participants

Reactant 2

HCID 6657Alpha-Aminobutyric Acid

HCID 7918Acetic Anhydride

Product 1

HCID 3061072-(Acetylamino)butanoic acid

Procedure

163 g (1.58 mol) of 2-aminobutyric acid are reacted analogously to Example 1A with 242 g (2.37 mol) of acetic anhydride to give 2-(acetylamino)butanoic acid.

Sources & evidence

ORD record: ord-22fe20fe55204d5bad4a332d0e7b19db
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573263B2

Reaction notes

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