Acetone → 6-Methyl-2-heptanone

HRID 1370775

Reaction equation

HRID 1370775 reaction equation
[CH:1](=O)[CH2:2][CH:3]([CH3:5])[CH3:4].[CH3:7][C:8]([CH3:10])=[O:9]>>[CH3:4][CH:3]([CH3:5])[CH2:2][CH2:1][CH2:7][C:8](=[O:9])[CH3:10]

Participants

3

Reactant 2

HCID 180AcetoneHCID 115523-Methylbutanal

Product 1

HCID 135726-Methyl-2-heptanone

Procedure

To aid comprehension, the reaction will be explained here by the example of the reaction of acetone with isovaleraldehyde to produce 6-methylheptan-2-one. The reaction takes place “in situ” via the stage of aldol condensation with the formation of the corresponding β-hydroxyketone, which is not isolated. Dehydration to 6-methylhept-3-en-2-one takes place under the reaction conditions, and this is hydrogenated selectively to the corresponding methylketone with the hydrogenation catalyst distributed homogeneously in the aqueous catalyst phase.

Workup

  1. customthe reaction

Sources & evidence

ORD record
ord-f282adfabe8d45cda6642831763bf31f
Source dataset
uspto-grants-2003_06
Patent number
US06583323B2

Linked notes

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