Potassium Hydroxide → 3-(4-(Propan-2-yloxy)phenyl)propanoic acid
Reaction equation
C[O:2][C:3](=[O:20])[CH:4]([CH2:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH:17]([CH3:19])[CH3:18])=[CH:12][CH:11]=1)C(OC)=O.[OH-].[K+]>C(O)C>[CH3:19][CH:17]([O:16][C:13]1[CH:14]=[CH:15][C:10]([CH2:9][CH2:4][C:3]([OH:20])=[O:2])=[CH:11][CH:12]=1)[CH3:18]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2-[[4-(1-Methylethoxy)phenyl]methyl]-propanedioic acid dimethyl ester (23.6 g, 84.2 mmol) is stirred into 2N potassium hydroxide solution (15 ml)/ethanol (25 ml) for 18 hours at boiling temperature.
Sources & evidence
- ORD record
- ord-984495e727844896929ba5089746f597
- Source dataset
- uspto-grants-2007_01
- Patent number
- US07166588B2
Reaction notes
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