Acrylonitrile → 4,4-Diacetylheptanedinitrile
Reaction equation
[OH-].[K+].[CH3:3][C:4](=[O:9])[CH2:5][C:6](=[O:8])[CH3:7].[C:10](#[N:13])[CH:11]=[CH2:12]>CO>[C:6]([C:5]([C:4](=[O:9])[CH3:3])([CH2:12][CH2:11][C:10]#[N:13])[CH2:12][CH2:11][C:10]#[N:13])(=[O:8])[CH3:7]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
After addition of 0.25 g of KOH, dissolved in 2.5 ml of methanol, to 15.0 g of 2,4-pentandione, 35.0 g of acrylonitrile was added dropwise with the reaction temperature not exceeding 40° C. The product which was precipitated during the process was filtered off, washed with a small amount of acetone, and dried. Melting point: 185–186° C. Purity>98%. The product was colorless.
Workup
- additionwas added dropwise with the reaction temperature not
- customexceeding 40° C
- customThe product which was precipitated during the process
- filtrationwas filtered off
- washwashed with a small amount of acetone
- customdried
Sources & evidence
- ORD record
- ord-758eda3c20a4438ca313d26eead9b2f5
- Source dataset
- uspto-grants-2007_01
- Patent number
- US07166648B2
Reaction notes
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