Gamma-undecalactone → Sodium 4-hydroxyundecanoate
Reaction equation
[OH-:1].[Na+:2].[CH3:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]1[O:15][C:13](=[O:14])[CH2:12][CH2:11]1>CO>[Na+:2].[OH:15][CH:10]([CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH3:3])[CH2:11][CH2:12][C:13]([O-:14])=[O:1]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 43.6 g of sodium hydroxide in 150 ml of methanol heated to reflux, 200 g of gamma-undecalactone was dropped in. After stirring for 2 hours at reflux, the mixture was cooled to room temperature and evaporated to dryness. The resulting crystals were washed with hexane to yield 240 g of colorless crystals.
Workup
- temperatureto reflux
- temperatureat reflux
- customevaporated to dryness
- washThe resulting crystals were washed with hexane
Sources & evidence
- ORD record
- ord-87da73d642824bfba22932a45e708111
- Source dataset
- uspto-grants-2001_07
- Patent number
- US06258854B1
Reaction notes
Loading…