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Benzhydrylamine → HCID 20292080, compound

HRID 1389207
Notes
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Reaction equation

HRID 1389207 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8].[CH:12]([NH2:25])([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1CCCCC1>[CH2:10]([O:9][C:7](=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:25][CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:11]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 7036BenzhydrylamineHCID 117544Ethyl 6-bromohexanoate

Product 1

HCID 20292080HCID 20292080, compoundYield 69.2%

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

22.3 g of ethyl 6-bromocaproate, 55 g of benzhydrylamine and 30 ml of cyclohexane are stirred at room temperature for 20 days. Preparation analogously to Example 19 yields 22.5 g (69% of theory) of ethyl-6-benzhydrylaminocaproate [B.P. 162° to 167° (0.02 mm Hg)].

Workup

  • customPreparation analogously to Example 19
  • Sources & evidence

    ORD record
    ord-e93d4cf90b284110a4ccdcd128247057
    Source dataset
    uspto-grants-1981_01
    DOI
    10.6084/m9.figshare.5104873.v1
    Patent number
    US04243678

    Reaction notes

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    On this pageParticipantsProcedureWorkupSources & evidenceReaction notes