2-Methyl-3-tert.-butoxypropan-1-ol → 1-Bromo-3-tert-butoxy-2-methylpropane

Reaction equation

[C:1]([O:5][CH2:6][CH:7]([CH3:10])[CH2:8]O)([CH3:4])([CH3:3])[CH3:2].[Br:11]Br.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>>[C:1]([O:5][CH2:6][CH:7]([CH3:10])[CH2:8][Br:11])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 125367792-Methyl-3-tert.-butoxypropan-1-ol

HCID 44191054Bromine triphenylphosphine

Product 1

HCID 129232901-Bromo-3-tert-butoxy-2-methylpropane

Procedure

Reaction of rac.-3-tert. butoxy-2-methyl-1-propanol with bromine-triphenylphosphine using the procedure of Example 2 gave rac.-3-tert. butoxy-2-methyl-1-bromopropane as a colorless liquid, b.p. 67-77° C. (bath temperature) (9 mm Hg.)

Sources & evidence

ORD record: ord-4f2089f6dfaf4559aac17b8fef06d12d
Source dataset: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04140702

Reaction notes

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