Ethyl isothiocyanate → HCID 178465508, compound
Reaction equation
[NH:1]1[C:9]2[CH2:8][CH2:7][NH:6][CH2:5][C:4]=2[N:3]=[CH:2]1.[CH2:10]([N:12]=[C:13]=[S:14])[CH3:11]>C(#N)C>[CH2:10]([NH:12][C:13]([N:6]1[CH2:7][CH2:8][C:9]2[NH:1][CH:2]=[N:3][C:4]=2[CH2:5]1)=[S:14])[CH3:11]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 1.85 g of 4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine and 2 g of ethyl isothiocyanate in 15 ml of acetonitrile are refluxed for 7 h. The solution is cooled and filtered: 2.5 g of 5-[N-ethyl-thiocarbamoyl]-4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine, m.p. 185°, are collected.
Workup
- temperatureThe solution is cooled
- filtrationfiltered
- custom2.5 g of 5-[N-ethyl-thiocarbamoyl]-4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine, m.p. 185°, are collected
Sources & evidence
- ORD record
- ord-a6e00b8e4b894491b68e41761719e065
- Source dataset
- uspto-grants-1979_02
- Patent number
- US04141899
Reaction notes
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