Thiazolidinedione → 5-[5-(2-Chlorophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione

HRID 1394151

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:12][C:11]([CH:13]=O)=[CH:10][CH:9]=1.[S:15]1[CH2:19][C:18](=[O:20])[NH:17][C:16]1=[O:21]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:12][C:11](/[CH:13]=[C:19]2/[C:18](=[O:20])[NH:17][C:16](=[O:21])[S:15]/2)=[CH:10][CH:9]=1

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 6098215-(2-Chlorophenyl)furfural

Product 1

HCID 57652815-[5-(2-Chlorophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione

Procedure

The titled compound was prepared by the condensation of 5-(5-(2-chloro-phenyl)furan-2-aldehyde (1.0 g) with 2,4-thiazolidinedione (0.68 g) using the procedure described in Step B of EXAMPLE 1.

Sources & evidence

ORD record: ord-ecab8917b11145d89281d852eae19fe9
Source dataset: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07348348B2

Linked notes

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