HCID 3013671, compound → HCID 3013672, compound
Reaction equation
C(OC([N:11]1[CH2:16][CH2:15][CH:14]([C:17]([N:19]([CH2:26][CH2:27][CH2:28][N:29]2[CH2:34][CH2:33][CH:32]([CH2:35][C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)[CH2:31][CH2:30]2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:18])[CH2:13][CH2:12]1)=O)C1C=CC=CC=1>CO.[C].[Pd]>[CH2:35]([CH:32]1[CH2:33][CH2:34][N:29]([CH2:28][CH2:27][CH2:26][N:19]([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:17]([CH:14]2[CH2:15][CH2:16][NH:11][CH2:12][CH2:13]2)=[O:18])[CH2:30][CH2:31]1)[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1Participants
4
Reagents, catalysts & solvents 2
Procedure
The compound obtained in Example 1 (2.32 g, 4.2 mmol) was dissolved in methanol (30 ml). To the solution was added 10% palladium carbon (water content:50%, 0.93 g), and the mixture was subjected to catalytic hydrogenation reaction at room temperature for 16 hours. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give the titled compound (1.70 g, 4.1 mmol, Yield 97%).