Cyclohexylamine → 1-Cyclohexyl-3-methylurea

HRID 1395263

Reaction equation

HRID 1395263 reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[CH:5]1([NH2:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1>C(OCC)C>[CH3:1][NH:2][C:3]([NH:11][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)=[O:4]

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 12228Methyl Isocyanate

Product 1

HCID 3083441-Cyclohexyl-3-methylureaYield 67.3%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In 500 ml of ethyl ether is dissolved 57 g of methyl isocyanate and, then, 99 g of cyclohexylamine is added dropwise, whereupon crystals separate. The crystals are washed with ether. By the above procedure is obtained 105 g of N-methyl-N'-cyclohexylurea. melting point: 160°-161° C.

Workup

  1. customseparate
  2. washThe crystals are washed with ether

Sources & evidence

ORD record
ord-d70b5782e8ec4703bdfce9baa73e4c1c
Source dataset
uspto-grants-1980_05
Patent number
US04202975

Linked notes

Loading…