2-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acid → 2-Methyl-5-phenyl-oxazole-4-carboxylic Acid {2-[4-(1,1-difluoro-ethyl)-oxazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

HRID 139776Notes

Reaction equation

HRID 139776 reaction equation
[CH3:17][c:18]1[o:19][c:20](-[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:21]([C:23](=[O:24])[OH:25])[n:22]1.[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH2:16])[n:15]2)[o:8][cH:9]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH:16][C:23]([c:21]3[c:20](-[c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)[o:19][c:18]([CH3:17])[n:22]3)=[O:24])[n:15]2)[o:8][cH:9]1

Participants

3

Reactant 2

HCID 156303442-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acidHCID 671278932-[4-(1,1-Difluoro-ethyl)-oxazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 498342672-Methyl-5-phenyl-oxazole-4-carboxylic Acid {2-[4-(1,1-difluoro-ethyl)-oxazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

Sources & evidence

ORD record
ord-123316a0b58b415ca89d5aac61c28bb2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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