Sodium Hydroxide → 2-(4-(Benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid
Reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[C:7]([C:10]3[C:15]([CH:16]([CH2:21][CH2:22][CH3:23])[C:17]([O:19]C)=[O:18])=[C:14]([CH3:24])[N:13]=[C:12]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)[N:11]=3)[CH:8]=[CH:9][C:2]1=2.[OH-].[Na+]>CO>[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[C:7]([C:10]3[C:15]([CH:16]([CH2:21][CH2:22][CH3:23])[C:17]([OH:19])=[O:18])=[C:14]([CH3:24])[N:13]=[C:12]([C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=4)[N:11]=3)[CH:8]=[CH:9][C:2]1=2Participants
4
Procedure
2 This compound was prepared according to general method D from methyl 2-(4-(benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.047 g; 0.113 mmol), sodium hydroxide 10N (0.113 mL; 1.13 mmol) in methanol (1.1 mL) to afford 0.037 g (79%) of the title compound as a white solid.