2-Thiophenecarboxaldehyde → HCID 59054370, compound

Reaction equation

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:13][C:14]([CH3:17])([NH2:16])[CH3:15].[S:18]1[CH:22]=[CH:21][CH:20]=[C:19]1[CH:23]=O>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:13][C:14]([CH3:17])([NH:16][CH2:23][C:19]1[S:18][CH:22]=[CH:21][CH:20]=1)[CH3:15]

Participants

Reactant 2

HCID 73642-Thiophenecarboxaldehyde

HCID 681517292-(1-Chloronaphthalen-2-yloxy)-1,1-dimethylethylamine

Product 1

HCID 59054370HCID 59054370, compoundYield 40%

Procedure

Prepared from 1-[(1-chloronaphthalen-2-yl)oxy]-2-methylpropan-2-amine and thiophen-2 carbaldehyde in 40% yield as a brown oil.

Sources & evidence

ORD record: ord-d5946a6c1fa54f6e94e274033d09d9d7
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906946B2

Reaction notes

Loading…