1-Methyl-1H-pyrrole-2-carbaldehyde → HCID 59054372, compound

Reaction equation

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:13][C:14]([CH3:17])([NH2:16])[CH3:15].[CH3:18][N:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[CH:24]=O>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:13][C:14]([CH3:17])([NH:16][CH2:24][C:20]1[N:19]([CH3:18])[CH:23]=[CH:22][CH:21]=1)[CH3:15]

Participants

Reactant 2

HCID 145041-Methyl-1H-pyrrole-2-carbaldehyde

HCID 681517292-(1-Chloronaphthalen-2-yloxy)-1,1-dimethylethylamine

Product 1

HCID 59054372HCID 59054372, compoundYield 39%

Procedure

Prepared from 1-[(1-chloronaphthalen-2-yl)oxy]-2-methylpropan-2-amine and methyl-1H-pyrrole-2-carbaldehyde in 39% yield as a red oil.

Sources & evidence

ORD record: ord-e8395bbfd1284b79999879871f7399e8
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906946B2

Reaction notes

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