1-Methyl-1H-pyrrole-2-carbaldehyde → HCID 59053596, compound

Reaction equation

[Cl-].[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[NH:13][CH2:14][CH2:15][NH3+:16].[CH3:17][N:18]1[CH:22]=[CH:21][CH:20]=[C:19]1[CH:23]=O>>[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[NH:13][CH2:14][CH2:15][NH:16][CH2:23][C:19]1[N:18]([CH3:17])[CH:22]=[CH:21][CH:20]=1

Participants

Reactant 2

HCID 145041-Methyl-1H-pyrrole-2-carbaldehyde

HCID 68152103HCID 68152103, compound

Product 1

HCID 59053596HCID 59053596, compoundYield 47%

Procedure

Prepared from 2-[(1-chloronaphthalen-2-yl)amino]ethanaminium chloride and 1-methyl-1H-pyrrole-2-carbaldehyde in 47% yield as a white oil.

Sources & evidence

ORD record: ord-6dfdd534ec5f4ae58a03d8e968168bd2
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906946B2

Reaction notes

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