3,5-Bis-trifluoromethylphenylboronic acid → 4-[5-[3,5-bis(trifluoromethyl)phenyl]benzimidazol-1-yl]-N-(1-phenylethyl)pyrimidin-2-amine
Reaction equation
[F:26][C:27]([c:28]1[cH:29][c:30]([B:38]([OH:39])[OH:40])[cH:31][c:32]([C:34]([F:35])([F:36])[F:37])[cH:33]1)([F:41])[F:42].[c:1]1([CH:7]([CH3:8])[NH:9][c:10]2[n:11][cH:12][cH:13][c:14](-[n:16]3[cH:17][n:18][c:19]4[c:20]3[cH:21][cH:22][c:23]([I:25])[cH:24]4)[n:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH3:8])[NH:9][c:10]2[n:11][cH:12][cH:13][c:14](-[n:16]3[cH:17][n:18][c:19]4[c:20]3[cH:21][cH:22][c:23](-[c:30]3[cH:29][c:28]([C:27]([F:26])([F:41])[F:42])[cH:33][c:32]([C:34]([F:35])([F:36])[F:37])[cH:31]3)[cH:24]4)[n:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-0ef7d39401c841f49aabb81562746780
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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