5-(4-Chlorophenyl)-2-furaldehyde → HCID 86713722, compound

HRID 1406057

Reaction equation

HRID 1406057 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][C:11]([CH:13]=[O:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1>O.[Ru](=O)=O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C@H:8]2[O:12][C@@H:11]([CH2:13][OH:14])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 6761845-(4-Chlorophenyl)-2-furaldehyde

Product 1

HCID 86713722HCID 86713722, compound

Reagents, catalysts & solvents 1

HCID 16211523Ruthenium dioxide hydrateCatalyst

Procedure

The requisite [cis-5-(4-chlorophenyl)tetrahydrofuran-2-yl]methanol was prepared by hydrogenation of 5-(4-chlorophenyl)furan-2-carbaldehyde in the presence of ruthenium(IV) oxide hydrate.

Sources & evidence

ORD record
ord-67b47eaeb0f34047ad27e142b7e8b7e5
Source dataset
uspto-grants-2014_12
Patent number
US08916564B2

Linked notes

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