Chloroform → 3-(Chloromethyl)-8-methyl-2-o-tolylquinoline

HRID 140845

Reaction equation

[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH2:19][OH:20])[c:9](-[c:12]3[c:13]([CH3:18])[cH:14][cH:15][cH:16][cH:17]3)[n:10][c:11]12.[Cl:25][CH:26]([Cl:27])[Cl:28].[S:21]([Cl:22])([Cl:23])=[O:24]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH2:19][Cl:23])[c:9](-[c:12]3[c:13]([CH3:18])[cH:14][cH:15][cH:16][cH:17]3)[n:10][c:11]12

Participants

Reactant 3

HCID 6212Chloroform

HCID 24386Thionyl Chloride

HCID 57707986(8-Methyl-2-o-tolylquinolin-3-yl)methanol

Product 1

HCID 575561733-(Chloromethyl)-8-methyl-2-o-tolylquinoline

Sources & evidence

ORD record: ord-03a9b70295f6470390a0989d4bfb4121
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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