Ethoxalyl chloride → 5-Cyano-N-(5-methoxythiazol-2-yl)-1'-(2-(methylamino)-2-oxoacetyl)spiro[indoline-3,3'-pyrrolidine]-1-carboxamide

Reaction equation

[C:1]([C:3]1[CH:4]=[C:5]2[C:11]3([CH2:15][CH2:14][N:13]([C:16]([O:18]C(C)(C)C)=O)[CH2:12]3)[CH2:10][NH:9][C:6]2=[CH:7][CH:8]=1)#[N:2].Cl[C:24](=[O:30])C(OCC)=O.[NH2:31][C:32]1[S:33][C:34]([O:37][CH3:38])=[CH:35][N:36]=1.[CH3:39][NH2:40].[O:41]1[CH2:45]CCC1>>[C:1]([C:3]1[CH:4]=[C:5]2[C:11]3([CH2:15][CH2:14][N:13]([C:16](=[O:18])[C:45]([NH:40][CH3:39])=[O:41])[CH2:12]3)[CH2:10][N:9]([C:24]([NH:31][C:32]3[S:33][C:34]([O:37][CH3:38])=[CH:35][N:36]=3)=[O:30])[C:6]2=[CH:7][CH:8]=1)#[N:2]