Potassium Hydroxide → HCID 22814613, compound
Reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([NH:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=O)=[O:7])=[CH:4][CH:3]=1.[NH:17]1[CH2:26][CH2:25][CH2:24][C@H:18]1[C:19]([O:21]CC)=[O:20].[OH-].[K+]>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:8][CH2:9][CH2:10][CH2:11][C:12]([N:17]2[CH2:26][CH2:25][CH2:24][C@H:18]2[C:19]([OH:21])=[O:20])=[O:14])=[O:7])=[CH:15][CH:16]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-4-aminobutyric acid and ethyl L-prolinate and suitable processing, dissolving the evaporation residue in ethanol, adding an ethanolic solution of potassium hydroxide, stirring for 12 hours at room temperature and further processing yields N-[N-(p-chlorobenzoyl)-4-aminobutyryl]-L-proline.