1-(5-Chloro-2-methoxyphenyl)ethanone → 2-(5-Chloro-2-methoxyphenyl)propan-2-ol

HRID 1413861Notes

Reaction equation

HRID 1413861 reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[O:11][CH3:12])=[O:3].F[C:14]1C=CC(OC)=C(C(O)(C)C)C=1>>[Cl:10][C:8]1[CH:7]=[CH:6][C:5]([O:11][CH3:12])=[C:4]([C:2]([OH:3])([CH3:14])[CH3:1])[CH:9]=1

Participants

3

Reactant 2

HCID 2404341-(5-Chloro-2-methoxyphenyl)ethanoneHCID 222848882-(5-Fluoro-2-methoxyphenyl)propan-2-ol

Product 1

HCID 202911052-(5-Chloro-2-methoxyphenyl)propan-2-ol

Procedure

2-(5-chloro-2-methoxyphenyl)propan-2-ol (m.p. 56° C.) was prepared from 5-chloro-2-methoxyacetophenone following the method described in Example 3 for the preparation of 2-(5-fluoro-2-methoxyphenyl)propan-2-ol.

Sources & evidence

ORD record
ord-9b6af3abb3a3488c84b96f180e7137d3
Source dataset
uspto-grants-1981_02
Patent number
US04251546

Reaction notes

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