1-(3-Allyl-2,4-dihydroxyphenyl)ethanone → 2',4'-Dihydroxy-3'-propylacetophenone
Reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[C:6]([CH2:11][CH:12]=[CH2:13])[C:5]=1[OH:14])=[O:3]>C(O)C>[CH3:13][CH2:12][CH2:11][C:6]1[C:5]([OH:14])=[C:4]([C:2]([CH3:1])=[O:3])[CH:9]=[CH:8][C:7]=1[OH:10]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Dissolve 9.6 gm of 3-allyl-2,4-dihydroxyacetophenone in 100 ml of ethanol; flush with nitrogen and add 0.5 gm of 5% palladium/charcoal catalyst. Hydrogenate in a Parr apparatus at room temperature until 45 p.s.i. of hydrogen is taken up. Filter and strip the filtrate to dryness to obtain the title product. (mp 125°-127° C.)
Workup
- customflush with nitrogen
- additionadd 0.5 gm of 5% palladium/charcoal catalyst
- customat room temperature
- filtrationFilter
Sources & evidence
- ORD record
- ord-3717110c4f2f4ce2abc5558c367bfe83
- Source dataset
- uspto-grants-1981_02
- Patent number
- US04252818
Reaction notes
Loading…