Epibromohydrin → HCID 21488028, compound
Reaction equation
[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)=[O:7])=[CH:4][CH:3]=1.[CH2:26]([CH:28]1[O:30][CH2:29]1)Br>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:26][CH:28]3[O:30][CH2:29]3)=[CH:19][CH:18]=2)=[O:7])=[CH:24][CH:25]=1Participants
3
Procedure
When an equivalent amount of 3-p-chlorobenzoyl-2-p-hydroxyphenylbenzofuran was reacted with epibromohydrin as described in the procedure of Example 26 and the product 3-(4'-chlorobenzoyl)-2-[4'-(2,3-epoxypropoxy)phenyl]benzofuran thus formed was treated with isopropylamine as described in the procedure of Example 25, the title compound was obtained.
Sources & evidence
- ORD record
- ord-7fe51d197b6f4325bdbe781514c2e656
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04001426