Sodium Acetate → Benzophenone-4-maleimide

HRID 1417355

Reaction equation

HRID 1417355 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:17])/[CH:12]=[CH:13]\[C:14](O)=[O:15])=[CH:6][CH:5]=1)([OH:3])=O.[C:18](O)(=O)/[CH:19]=[CH:20]\[C:21](N)=O.[C:26]([O-])(=O)[CH3:27].[Na+]>C(OC(=O)C)(=O)C>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[C:11](=[O:17])[CH:12]=[CH:13][C:14]2=[O:15])=[CH:6][CH:5]=1)(=[O:3])[C:18]1[CH:27]=[CH:26][CH:21]=[CH:20][CH:19]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 5280451Maleamic acidHCID 5717537(Z)-4-(3-carboxyacrylamido)benzoic acid

Product 1

HCID 146390Benzophenone-4-maleimide

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

The method of Example 2 was employed, but, in place of the product of Example 1 the maleamic acid from Example 3 (15.0 g, 0.0508 mol) and anhydrous sodium ethanoate (3.00 g) in ethanoic anhydride (150 ml) were used. The maleimide was obtained. 1H-n.m.r (DMSO): δ 7.91 (4H, m, N-Ph); 7.52 (5H, m, Ph); 6.89 (2H, s, CH=CH), H.p.l.c. 100%.

Sources & evidence

ORD record
ord-06d5da891081497eb705befa26400766
Source dataset
uspto-grants-1999_03
Patent number
US05877204

Linked notes

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