Methanol → Methyl 2-chloropyridine-4-carboxylate

HRID 141745

Reaction equation

HRID 141745 reaction equation
[CH3:15][OH:16].[CH3:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Cl:5][c:6]1[cH:7][c:8]([C:9](=[O:10])[OH:11])[cH:12][cH:13][n:14]1.[Na+:18].[OH-:17].[OH2:26].[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:5][c:6]1[cH:7][c:8]([C:9](=[O:10])[O:11][CH3:15])[cH:12][cH:13][n:14]1

Participants

8

Reactant 7

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 1140TolueneHCID 24386Thionyl ChlorideHCID 2369852-Chloroisonicotinic acid

Product 1

HCID 2736842Methyl 2-chloropyridine-4-carboxylate

Sources & evidence

ORD record
ord-1e4b3a8cbe654911b7f4a461e6621f8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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