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Potassium Hydroxide → HCID 178493560, compound

HRID 1418818
Notes
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Reaction equation

HRID 1418818 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([SH:11])[N:4]=1.[OH-].[K+].[N+]([N:17]1[CH:21]=[C:20]([N+:22]([O-:24])=[O:23])[C:19]([CH3:25])=[N:18]1)([O-])=O>O.C(O)C>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([S:11][C:21]2[NH:17][N:18]=[C:19]([CH3:25])[C:20]=2[N+:22]([O-:24])=[O:23])[N:6]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

6

Reactant 3

HCID 14797Potassium HydroxideHCID 39944183-Methyl-1,4-dinitropyrazoleHCID 178493561HCID 178493561, compound

Product 1

HCID 178493560HCID 178493560, compoundYield 78.5%

Reagents, catalysts & solvents 2

HCID 702EthanolSolvent
HCID 962
Water
Solvent

Procedure

4,6-Dimethoxy-2-mercaptopyrimidine (4.65 g) was dissolved in water containing potassium hydroxide (1.7 g in 75 mls of water). 1,4-Dinitro-3-methylpyrazole (4.65 g) dissolved in the minimum of ethanol was then added dropwise. After the exothermic reaction had subsided, the mixture was stirred for 45 minutes. The precipitated solid was filtered off, washed with fresh water, and dried to give 6.3 g of the desired product, mp 175°-6° C.

Workup

  1. additionwas then added dropwise
  2. customAfter the exothermic reaction
  3. filtrationThe precipitated solid was filtered off
  4. washwashed with fresh water
  5. customdried

Sources & evidence

ORD record
ord-fcfabdb85eb14ddbb774715b2f92a40d
Source dataset
uspto-grants-1999_03
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US05885935

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes