Benzeneselenol → 2,4(1H,3H)-Pyrimidinedione, 5-(1-methylethyl)-1-((phenylmethoxy)methyl)-6-(phenylseleno)-

HRID 1419781

Reaction equation

HRID 1419781 reaction equation
[CH2:1]([O:8][CH2:9][N:10]1[C:17](Cl)=[C:16]([CH:19]([CH3:21])[CH3:20])[C:14](=[O:15])[NH:13][C:11]1=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:22]1([SeH:28])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.CC1C=C([SeH])C=C(C)C=1>>[CH2:1]([O:8][CH2:9][N:10]1[C:17]([Se:28][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:16]([CH:19]([CH3:21])[CH3:20])[C:14](=[O:15])[NH:13][C:11]1=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 69530BenzeneselenolHCID 107572371-[(Benzyloxy)methyl]-6-chloro-5-isopropyluracilHCID 1317212093,5-Dimethylphenyl selenol

Product 1

HCID 4630392,4(1H,3H)-Pyrimidinedione, 5-(1-methylethyl)-1-((phenylmethoxy)methyl)-6-(phenylseleno)-Yield 92%

Procedure

The titled compound was prepared in the same manner as described in Example 34 B by using 1-[(benzyloxy)methyl]-6-chloro-5-isopropyluracil and benzeneselenol in place of 6-chloro-1-(ethoxymethyl)-5-isopropyluracil and 3,5-dimethylphenyl selenol.

Sources & evidence

ORD record
ord-0dc3eddc143148188f044e5ad33d39e2
Source dataset
uspto-grants-1999_03
Patent number
US05889013

Linked notes

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