Benzeneselenol → 1-Butyl-6-[(3,5-dimethylphenyl)selenenyl]-5-isopropyl-2-thiouracil

HRID 1419783

Reaction equation

HRID 1419783 reaction equation
[CH2:1]([N:5]1[C:12](S(C)=O)=[C:11]([CH:16]([CH3:18])[CH3:17])[C:9](=[O:10])[NH:8][C:6]1=[S:7])[CH2:2][CH2:3][CH3:4].[CH3:19][C:20]1[CH:21]=[C:22]([SeH:27])[CH:23]=[C:24]([CH3:26])[CH:25]=1.C1([SeH])C=CC=CC=1>>[CH2:1]([N:5]1[C:12]([Se:27][C:22]2[CH:23]=[C:24]([CH3:26])[CH:25]=[C:20]([CH3:19])[CH:21]=2)=[C:11]([CH:16]([CH3:18])[CH3:17])[C:9](=[O:10])[NH:8][C:6]1=[S:7])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 3

HCID 69530BenzeneselenolHCID 105413891-Butyl-5-isopropyl-6-(methylsulfinyl)-2-thiouracilHCID 1317212093,5-Dimethylphenyl selenol

Product 1

HCID 108353331-Butyl-6-[(3,5-dimethylphenyl)selenenyl]-5-isopropyl-2-thiouracilYield 88%

Procedure

The titled compound was prepared in the same manner as described in Example 39 by using 1-butyl-5-isopropyl-6-(methylsulfinyl)-2-thiouracil and (3,5-dimethylphenyl) selenol in place of 1-(4-acetoxybutyl)-5-ethyl-6-(methylsulfinyl)-2-thiouracil and benzeneselenol, respectively.

Sources & evidence

ORD record
ord-f8339385320943dabf39028184025100
Source dataset
uspto-grants-1999_03
Patent number
US05889013

Linked notes

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