2-Chloro-5-methylpyrimidine → Benzyl 4-{[(5-methyl-2-pyrimidinyl)amino]methyl}-1-piperidinecarboxylate

HRID 142144

Reaction equation

HRID 142144 reaction equation
[Cl:19][c:20]1[n:21][cH:22][c:23]([CH3:26])[cH:24][n:25]1.[NH2:1][CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:7][CH2:8]1>>[NH:1]([CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:7][CH2:8]1)[c:20]1[n:21][cH:22][c:23]([CH3:26])[cH:24][n:25]1

Participants

3

Reactant 2

HCID 5817192-Chloro-5-methylpyrimidineHCID 219554994-Aminomethyl-1-N-Cbz-piperidine

Product 1

HCID 9881091Benzyl 4-{[(5-methyl-2-pyrimidinyl)amino]methyl}-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-8be6fabd7e974f239d8f114811276365
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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