N-bromobutanimide → HCID 68405898, compound
Reaction equation
[CH3:1][C:2]1[NH:6][C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[N:4][CH:3]=1.C1C(=O)N([Br:19])C(=O)C1>>[Br:19][C:3]1[N:4]=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[NH:6][C:2]=1[CH3:1]Participants
3
Procedure
The same operation as in Example (1c) was performed using ethyl 5-methyl-1H-imidazole-2-carboxylate obtained by the method described in Example (5a) (0.30 g, 1.95 mmol) and NBS (0.35 g, 1.96 mmol), to obtain 0.43 g of the title compound as a white solid (94%).
Workup
- customobtained by the method
Sources & evidence
- ORD record
- ord-5d7a2877e4a8420aae1b3eb03c7104f3
- Source dataset
- uspto-grants-2015_01
- Patent number
- US08927588B2
Reaction notes
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