4-Bromo-2-fluoroanisole → 8-(3-Fluoro-4-methoxyphenyl)-1,4-dioxaspiro[4.5]decan-8-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:10])[c:5]([O:8][CH3:9])[cH:6][cH:7]1.[O:11]1[CH2:12][CH2:13][O:14][C:15]12[CH2:16][CH2:17][C:18](=[O:21])[CH2:19][CH2:20]2>>[c:2]1([C:18]2([OH:21])[CH2:17][CH2:16][C:15]3([O:11][CH2:12][CH2:13][O:14]3)[CH2:20][CH2:19]2)[cH:3][c:4]([F:10])[c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-3b6645b489da4b27bad66ba8fd4c7d54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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