3-Chloro-2-hydroxybenzaldehyde → 6-[4-(3-Chloro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

HRID 143665

Reaction equation

HRID 143665 reaction equation
[Cl:14][c:15]1[c:16]([OH:23])[c:17]([CH:18]=[O:19])[cH:20][cH:21][cH:22]1.[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][N:4]([CH2:18][c:17]2[c:16]([OH:23])[c:15]([Cl:14])[cH:22][cH:21][cH:20]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 5196513-Chloro-2-hydroxybenzaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one

Product 1

HCID 1361025806-[4-(3-Chloro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

Sources & evidence

ORD record
ord-db003e0ecb9941a2a8f60bac58970daf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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