Ethyl 2-Formylpropionate → HCID 23334400, compound

HRID 1438712Notes

Reaction equation

HRID 1438712 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[CH2:5][NH:6][NH2:7].C([O:14][C:15](=O)[CH:16]([CH:18]=O)[CH3:17])C>C(O)C>[CH3:18][C:16]1[C:15](=[O:14])[N:6]([CH2:5][C:4]2[CH:8]=[CH:9][C:10]([Cl:11])=[C:2]([Cl:1])[CH:3]=2)[NH:7][CH:17]=1

Participants

4

Reactant 2

HCID 10898741Ethyl 2-FormylpropionateHCID 20495842HCID 20495842, compound

Product 1

HCID 23334400HCID 23334400, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10.9 g of 3,4-dichlorobenzylhydrazine were added dropwise to a solution of 7.5 g of a α-formylpropionic acid ethyl ester in 50 ml of ethanol. After stirring overnight at room temperature, the solvent was distilled off in vacuo and the solid residue was recrystallized from ethanol.

Workup

  1. distillationthe solvent was distilled off in vacuo
  2. customthe solid residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-d699554e894d441981b613cd6eab6b1f
Source dataset
uspto-grants-1977_11
Patent number
US04056533

Reaction notes

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