(4-Chlorophenyl)hydrazine → 2-(4-chloro-2-fluorophenyl)-1,4,5,6-tetrahydrocyclopentapyrazol-3(2H)-one

Reaction equation

ClC1C=CC(NN)=CC=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17][NH2:18])=[C:13]([F:19])[CH:12]=1.ClC1C=CC(N2[C:31](=[O:32])[C:30]3[CH2:33][CH2:34][CH2:35][C:29]=3N2)=CC=1>>[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([N:17]2[C:31](=[O:32])[C:30]3[CH2:33][CH2:34][CH2:35][C:29]=3[NH:18]2)=[C:13]([F:19])[CH:12]=1

Participants

Reactant 3

HCID 70624(4-Chlorophenyl)hydrazine

HCID 2782934(4-Chloro-2-fluorophenyl)hydrazine

HCID 17168663HCID 17168663, compound

Product 1

HCID 227622242-(4-chloro-2-fluorophenyl)-1,4,5,6-tetrahydrocyclopentapyrazol-3(2H)-one

Procedure

By substituting 4-chlorophenylhydrazine in the former procedure for 4-chloro-2-fluorophenylhydrazine, 2-(4-chlorophenyl)-1,4,5,6-tetrahydrocyclopentapyrazol-3(2H)-one was prepared, m.p. 193.5°-195°.

Workup

customwas prepared

Sources & evidence

ORD record: ord-5ea52d2d22e84d6b9a97823ee0c93ace
Source dataset: uspto-grants-1977_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04059434

Reaction notes

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